Drug points: Allopurinol interaction with cyclosporin
نویسندگان
چکیده
منابع مشابه
Drug interaction between sevelamer and cyclosporin.
Sir, Sevelamer hydrochloride is a calcium-free polymer licensed recently as a phosphate binder in haemodialysis (HD) patients. Its use is associated with a slower progression of coronary and aortic calcifications than the use of calciumbased binders in such patients [1]. Sevelamer not only binds phosphate but also bile acids, thereby reducing LDL cholesterol levels [2]. Whether this effect on t...
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Pyrazinamide (PZA) is increasingly used with isoniazid and rifampicin, in short-course antituberculous chemotherapy in service programme conditions. Complicating arthralgias occur due to hyperuricaemia induced by the inhibition of renal tubular secretion of uric acid by pyrazinoic acid, the main PZA metabolite. Allopurinol (Al), a hypouricaemic agent, provides no substantial clinical improvemen...
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Spectrophotometric micro determination of allopurinol (ALP) via charge-transfer formation is described. This includes the utility of some π-acceptors such as 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) and 3,6-dichloro-2,5-dihydroxy-p-benzoquinone (p-CLA) for estimation of ALP drug (act as è-donor). These reactions are applied for determination of ALP in its pharmaceutical preparations coming...
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range of other conditions, including Another important aspect in its distribution is that it is highly bound to psoriasis, rheumatoid arthritis, and erythrocytes and plasma lipoproteins. At low blood concentrations (below asthma 80 nmolIl (100 ng/ml)) and when the packed cell volume is low (for example, in patients with kidney failure) the contribution of the plasma bound fraction becomes more ...
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هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
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ژورنال
عنوان ژورنال: BMJ
سال: 1994
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.308.6921.113c